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Alzheimer's & Dementia
Interesting new developments have occurred over the past four years on how pulsed magnetic fields might play a significant part in off-setting the progression of dementia.
Thankfully something that is relatively easy to regulate could help the many millions of people coping with dementia on a daily basis.
We will keep looking at these ongoing developments and updating you on any significant findings. Whilst we cannot possibly claim that our Magneton is at all related to the pulsed devices being currently used; I for one, and quite happy to give Gaby and me a 5 minute session at night as we sit watch TV.
The area if the brain concerned in the trials was the left dorsolateral prefrontal cortex.
( Top of the left front)
Watch this space, I will try to get a fully qualified colleague to give us a few more pointers on the subject. In the meantime, please take a look at the following!
Magnetic pulse to head - could improve memory of dementia sufferers.
Alzheimer’s and Dementia.
Clinical Trails Positive Results seen using Pulsed Magnetic Devices.
Thursday June 24 2010
In Alzheimer's, abnormal protein tangles (red) form in brain cells “Applying magnets to the brains of Alzheimer's disease sufferers helps them understand what is said to them”, The Independent has claimed. The news is based on a small trial of an experimental magnetic therapy called rTMS, which some believe can reorganise brain cells and improve neurological functions. Over four weeks, five patients were given rTMS and five were given two weeks of sham treatment followed by two weeks of real rTMS. The rTMS was applied to the area of the brain known to be involved in speech and communication, which are often impaired during Alzheimer’s disease. After two weeks, those treated solely with rTMS showed improvements in sentence comprehension. Those receiving the sham treatment did not improve. The sham group then improved a similar amount after two weeks of real rTMS. Unfortunately, the technique did not improve other important language abilities, such as talking, cognitive function or memory. Equally, the design of this small study means that it cannot inform us about the long-term effects or potential harms from rTMS. While the use of rTMS in dementia will be of interest to neuroscientists, it should be seen as an experimental technique until larger, longer-term studies can evaluate it further. Where did the story come from? The study was carried out by researchers from the IRCCS Centro San Giovanni di Dio Fatebenefratelli and other educational and research institutes in Italy. This research was supported by a project grant from the Italian Ministry of Health and the Associazione Fatebenefratelli per la Ricerca (AFaR) research foundation. It was published in the peer-reviewed Journal of Neurology, Neurosurgery & Psychiatry. The other papers reporting this study, including The Daily Telegraph, have fairly represented the preliminary nature of this experimental research, and highlighted the fact that only 10 patients were treated. Some newspaper headlines and the scientists’ press release probably overstate the case presented by this small study by suggesting that the treatment “holds considerable promise”.
AND FROM THE USA
Scientists at Northwestern University in the US, found that stimulating parts of the brain with magnetic pulses to stimulate neurons improved memory by more than 20 per cent
Researchers used a technique called Transcranial Magnetic Stimulation which uses a magnetic pulse to trigger electrical charges in the brain cells, forcing them to become more active
By Sarah Knapton, Science Correspondent
6:00PM BST 28 Aug 2014
A simple magnetic pulse to the head could improve memory for Alzheimer’s disease sufferers or stroke patients, a study has found. Scientists at Northwestern University in the US, discovered that stimulating parts of the brain improved memory by more than 20 per cent. And the effects appear to last for several days after the treatment. "We show for the first time that you can specifically change memory functions of the brain in adults without surgery or drugs, “said senior author Dr Joel Voss, assistant professor of medical social sciences at Northwestern University Feinberg School of Medicine "This non-invasive stimulation improves the ability to learn new things. It has tremendous potential for treating memory disorders." Dementia charities said the breakthrough showed potential for treating Alzheimer’s disease. Researchers used a technique called Transcranial Magnetic Stimulation which uses a magnetic pulse to trigger electrical charges in the brain cells, forcing them to become more active. Dr Voss said it was like giving the brain regions a more talented conductor so they play in closer synchrony. They tested the memory of 16 volunteers between 21 and 40 who were all in good health. They then used a MRI machine to work out exactly which part of the brain was storing memories. Memories are stored in the hippocampus, an area in the middle of the brain roughly at eye level. But the exact area can differ by up to a centimetre between individuals. Although the hippocampus is too deep for magnetic fields to penetrate, the team found an area directly above it which has direct contact. Once they knew the exact area to target, the volunteers received brain stimulation 20 minutes a day for five consecutive days. The researchers discovered that the volunteers performed around 20 per cent better on memory tests compared with an untreated control group, who showed no improvement during the period. "They remembered more face-word pairings after the stimulation than before, which means their learning ability improved," Dr Voss said. "That didn't happen for the placebo condition or in another control experiment with additional subjects. . "The more certain brain regions worked together because of the stimulation, the more people were able to learn face-word pairings, " Voss said. They are hopeful the technique could be used to help the early symptoms of Alzheimer’s disease; depression, schizophrenia and other mental health problems. The current study was with people who had normal memory, who researchers did not expect to see a larger improvement because their brains are already working effectively. "But for a person with brain damage or a memory disorder, those networks are disrupted so even a small change could translate into gains in their function," Voss added. In an upcoming trial, he will study the electrical stimulation's effect on people with early-stage memory loss. Dr Simon Ridley, Head of Research at Alzheimer’s Research UK, the UK’s leading dementia research charity, said: “The results of this study shows some potential in the use of a non-invasive technique which may help to improve memory. This was a very small trial with only 16 people and did not look specifically at people with Alzheimer’s disease or other forms of dementia. Much more large-scale, long-term research is needed to determine whether this technique would be beneficial to people with dementia. “There is currently no effective treatment or cure for Alzheimer’s or dementia. We urgently need an effective treatment that could stop the The study was published in the journal Science. In a separate study, the University of Huddersfield has discovered that a key ingredient found in pomegranates could help slow the onset of Alzheimer’s disease. Dr Olumayokun Olajide found that punicalagin can prevent inflammation in brain cells. This inflammation leads to the destruction of more and more brain cells, making the condition of Alzheimer's sufferers progressively worse. The team is hopeful that a drug derived from punicalagin that could treat neuro-inflammation and slow the disease. There are currently 800,000 people with dementia in the UK and the number is rising progressively.